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Regularized Modal Regression with Applications in Cognitive Impairment Prediction
Author: Release time:2018-05-27 Number of clicks:

Title: Regularized Modal Regression with Applications in CognitiveImpairment Prediction

Speaker: Hong Chen

Affiliation: Huazhong Agricultural University

Time: 2018-5-28 10:00-11:00

Venue: Room 201 Lecture Hall

abstract:Linear regression models have been successfully used to function estimation and model selection in high-dimensional data analysis. However, most existing methods are built on least squares with the mean square error (MSE) criterion. In this talk, we go beyond this criterion by investigating the regularized modal regression from a statistical learning viewpoint. A new regularized modal regression model is proposed for estimation and variable selection, which is robust to outliers, heavy-tailed noise, and skewed noise. On the theoretical side, we establish the approximation estimate for learning the conditional mode function, the sparsity analysis for variable selection, and the robustness characterization. On the application side, we applied our model to improve the cognitive impairment prediction using the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort data.



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